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On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757636) and ShORe (OPT-302 with ranibizumab in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757610).2,3 These trials represent one of the largest phase […]

Carl Regillo, Hawaiian Eye 2022: Emerging Therapies for Wet Age-related Macular Degeneration

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Published Online: Feb 8th 2022

There are new treatment options for patients with wet age-related macular degeneration emerging, according to a presentation at Hawaiian Eye 2022. It was a pleasure to speak with Dr Carl Regillo (Thomas Jefferson University, Philadelphia, PA, USA) about his views on the latest treatments to emerge for wet age-related macular degeneration.

The abstract entitled Update on Emerging Wet AMD Therapies was presented at Hawaiian Eye 2022, 15–21 January 2022.  

Questions

  1. What is the current status of the clinical development of tyrosine kinase inhibitors in the treatment of wet age-related macular degeneration? (00:14)
  2. What other agents are emerging or in late stage clinical development? (02:02)

Speaker Disclosure: Carl Regillo has received speakers’ fees from Genentech, Allergan, Annexon, Novartis, Apellis, Iveric, NGM, Adverum, Regenxbio, Regeneron, Opthea, Thea.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Lisa Glass.

Filmed in coverage of Hawaiian Eye 2022.

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