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Eye Examination with High-Tech Ophthalmology Equipment. Patient undergoing an eye examination using advanced ophthalmology equipment with orange light, for accurate diagnostics.
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Hashem  Abu Serhan, Abdullah Ahmed, Barbara Parolini

Ophthalmologists, like all medical professionals, strive to base their practice on solid evidence. However, even in our field, certain beliefs have taken root more through tradition and repetition than through rigorous scientific scrutiny. Margolis and Galor published their editorial in which they debunked six myths related to the anterior segment.1 Their work motivated our critical thinking, […]

Arshad Khanani, ARVO 2022: RGX-314 gene therapy for neovascular age-related macular degeneration

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Published Online: Jun 27th 2022

An overview and the mechanism of action of RGX-314 is discussed in this touchOPHTHALMOLOGY interview with Prof. Arshad Khanani (Sierra Eye Associates, Reno, NV, USA) as well as the limitations of anti-VEGF therapy for neovascular AMD.

The presentation entitled ‘Suprachoroidal Delivery of RGX-314 Gene Therapy for Neovascular AMD: The Phase II AAVIATE™ Study’ was presented at the The Association for Research in Vision and Ophthalmology, May 01-04, 2022.

Questions:

  1. What are the limitations of anti-VEGF therapy for neovascular AMD?
  2. What is RGX-314 and what is its mechanism of action?

Disclosures: Arshad Khanani is a consultant for Regenxbio and discloses grant/research Support from Regenxbio.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Shanice Allen.

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