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On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757636) and ShORe (OPT-302 with ranibizumab in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757610).2,3 These trials represent one of the largest phase […]

Rahul Khurana, AAO 2022: Loss to follow-up in patients with nAMD treated with anti-VEGF therapy in the US

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Published Online: Oct 20th 2022

Dr Rahul Khurana (Northern California Retina Vitreous Associates, Mountain View, CA, USA) took part in a retrospective cohort study investigating the incidence of loss to follow-up after anti–vascular endothelial growth factor (VEGF) injections among patients with neovascular age-related macular degeneration. In this interview, he discusses with  touchOPHTHALMOLOGY the design and findings of this study as well as the factors affecting loss to follow-up after anti-VEGF therapy.  

The poster ‘Loss to Follow-Up in Patients With nAMD Treated With Anti-VEGF Therapy in the U.S.’ was presented at the annual American Academy of Ophthalmology (AAO) meeting, 30 September – 3 October 2022 

  1. What is the impact of loss to follow up after anti-vascular endothelial growth factor (anti-VEGF) injections among patients with neovascular age-related macular degeneration (nAMD)? (00:19)
  2. What were the objectives and design of your study? (00:46)
  3. What were the overall findings of the study? (01:11)
  4. What factors affected loss to follow up? (02:19)
  5. What interventions may improve outcomes? (02:50)

Disclosure: Rahul Khurana has nothing to disclose in relation to this video.

Support: Interview and filming supported by Touch Medical Media Ltd. Interview conducted by Lisa Glass.

Filmed as a highlight of AAO 2022.

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