SOE Highlights

On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757636) and ShORe (OPT-302 with ranibizumab in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757610).2,3 These trials represent one of the largest phase […]

Since its inception in November 2022, ChatGPT-3.5 has gained increasing popularity.1,2 ChatGPT is an artificial intelligence (AI) language application that performs online tasks and mimics human conversations using a question-and-answer format.3 The interface has found widespread use in several industries, with applications ranging from programming, business, education and healthcare.4 To contextualize this new technology, it is […]

The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part of the eye, such as the vitreous or peripheral retina. The clinical taxonomy of uveitis […]

Thermoreceptors on the ocular surface play a critical role in the development of dry eye disease (DED). An experimental eye drop called AR-15512, which activates cooling receptors, has been found to provide fast and continuous relief from dry eye symptoms, with minimal side effects. Due to its cold-sensing stimulation, this medication may also help patients […]

We are pleased to present the latest edition of touchREVIEWS in Ophthalmology. In this issue, we offer a series of engaging editorials, in-depth review articles and insightful original research highlighting some of the latest breakthroughs, innovations and practical insights in the dynamic field of ophthalmology. We begin with macular degeneration, where José-Alain Sahel et al. […]

Age-related macular degeneration (AMD) is a chronic deterioration and dysfunction of the outer retinal tissue and Bruch’s membrane (BrM). It is the leading cause of vision loss in people older than 60 years and is estimated to affect 288 million people by 2040 with 39 million new cases by 2050.1,2 AMD has the highest economic burden […]

Dry eye disease (DED) is a prevalent ocular condition characterized by discomfort, visual disturbances and tear film instability due to insufficient tear production or rapid tear evaporation.1 With an increasing global incidence (i.e. up to 50%) and its significant impact on the quality of life, there is a growing need for accurate and efficient diagnostic methods to […]

Thyroid eye disease (TED) is an autoimmune condition that can lead to significant visual impairment, facial disfigurement and decreased quality of life. It affects 16 out of every 100,000 females and 2.9 out of every 100,000 males. Risk factors for TED include age, female gender, smoking and radioactive iodine therapy.1 TED typically begins with a progressive […]

Contrast sensitivity (CS), which is an important element of functional vision, helps in differentiating an object from its background. CS affects several aspects of vision, such as acuity, dark adaptation, visual field, motion detection and pattern recognition.1 A decline in spatial CS occurs in several ophthalmic disorders, including cataract, glaucoma, diabetic retinopathy and age-related macular degeneration. Commonly, […]