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On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757636) and ShORe (OPT-302 with ranibizumab in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757610).2,3 These trials represent one of the largest phase […]

Bennie Jeng, WOC 2018 – Developing our Understanding of Dry Eye Disease

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Published Online: Jul 19th 2018

We met up with Editorial Board member Bennie Jeng, who updated us on the exciting recent developments in dry eye disease and several new therapies are in development in the US. Dr Jeng talked about his experience with scleral contact lenses, which have proved particularly useful for very severe dry eye patients with GVHD and Stevens-Johnson disease in his clinic. There is still unmet need for patients with chronic severe dry eye disease patients, including access to scleral contact lenses and also recognising and understanding neuropathic pain. A better understanding of the mechanisms behind dry eye disease will help to develop new treatments.

Questions:
1. What have been the most significant recent developments in the area of dry eye disease? (0:29)
2. Discuss the current unmet needs and/or the challenges you face when treating patients with dry eye disease. (1:53)
3. What developments are you most excited about in the area of dry eye disease over the next few years? (3:10)
4. Which presentations/data have interested you the most at this year’s WOC? (3:58)

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