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The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part of the eye, such as the vitreous or peripheral retina. The clinical taxonomy of uveitis […]

Qi Cui, AGS 2021: The GLP-1R Agonist NLY01 Reduces Neuroinflammation and Protects against RGC Loss in a Preclinical Glaucoma Model

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Published Online: Mar 5th 2021

We were delighted to catch up with Dr Qi Cui (Scheie Eye Institute, University of Pennsylvania, PA, USA), who told us about her research on the GLP-1R agonist NLY01 and the next steps for clinical development.

Questions

  1. What is NLY01 and what is the rationale for its use in glaucoma therapy? (00:20)
  2. Could you give us an overview of your study and its findings? (01:31)
  3. What will be the next steps in the clinical development of NLY01? (02:46)

Speaker Disclosure: Qi Cui discloses the following: Patent (pending): Penn Center for Innovation; Sponsored Research: Neuraly, Inc., NIH/NEI K08EY029765.

Support: Interview and filming supported by Touch Medical Media Ltd.

Filmed in coverage of AGS 2021.

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