Evaluation of Corneal Oedema – Tools we Have and Those Under Investigation

The treatment options for neurotrophic keratitis (NK) are ever-evolving as the pathogenesis of this increasingly prevalent degenerative keratopathy is further elucidated. Currently available therapeutics can be divided into medical, procedural and surgical interventions that directly address the effects of corneal ...

Acanthamoeba is an opportunistic, unicellular, free-living protist with at least 25 species and 23 genotypes so far identified (on 18S rRNA sequencing).1 Organisms have a two-stage life cycle: metabolically active trophozoites and quiescent double-walled cysts. Both trophozoites and cysts are small, usually 15–50 µ...

Neurotrophic keratitis (NK), also referred to as neurotrophic keratopathy, is a rare disease characterized by trigeminal nerve dysfunction, leading to a reduction or loss of corneal sensation and subsequent degenerative changes in the cornea.1 Deterioration starts when spontaneous breakdown of ...

Keratoconus is the most common corneal ectasia. It disproportionally affects children and adolescents and involves a focal weakening of the biomechanical integrity of the cornea.1 The disease typically manifests as a progressive thinning and bulging of the cornea, which causes ...

Varicella zoster virus is a double-stranded DNA herpesvirus that resides dormant in the sensory nerve ganglia after primary infection of varicella/chicken pox. While primary infection can be mild, on reactivation, the virus typically causes a painful vesicular rash called ...

Keratoconus is the most common primary progressive ectatic condition of the cornea. It is classically described as non-inflammatory, distinguishing it from several other pathologies associated with corneal thinning. Prevalence of this disease varies depending on geographical location, with reports as ...

Most surgical procedures are performed in the operating room, for obvious reasons. Operating rooms are sterile, they should be stocked with all of the equipment and materials you might need, and the operating-room staff are trained and ready to assist ...

Dominique Bremond-Gignac, MD, PhD, FEBO, is Professor of Ophthalmology and Head of the Department of Ophthalmology with a paediatric and ocular surface subspecialty at the University Hospital Necker–Enfants Malades and University of Paris in Paris, France. She graduated in ...

I was interested to read the review, “Optical Lens Tinting—A Review of its Functional Mechanism, Efficacy, and Applications” by Jared Raabe, Ashwini Kini, and Andrew Lee, which appeared in US Ophthalmic Review.1 I am the inventor of the FL–41 ...

Proparacaine is a topical anesthetic widely used in ophthalmic practice. Proparacaine is well tolerated with limited duration of use, but has potential to become a drug of abuse.1 Extended use has numerous corneal sequelae including stromal infiltrates, corneal melt, and ...

The health of the corneal endothelium, the innermost single cell layer of the cornea, is essential in maintaining corneal transparency. This is achieved through a passive diffusion of fluid across leaky inter-cellular tight junctions from the aqueous humor into the ...

Infectious crystalline keratopathy (ICK) is an uncommon and indolent infection classically characterized by densely packed branching opacities in the absence of a robust inflammatory response. This infection is most often seen in the setting of prior corneal surgery, particularly penetrating ...