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Corneal ectatic disorders, such as keratoconus, progressively weaken corneal integrity, leading to thinning, irregular astigmatism and visual deterioration.1 Typically progressive in nature, these ectasias result in increasingly thinner corneas, causing the cornea to protrude forward into a cone shape. This leads to increasing amounts of myopia and astigmatism – both regular and irregular – as the disease […]

Published Online: Sep 10th 2025

Insights from the touchOPHTHALMOLOGY Future Leaders 2025

As the landscape of ophthalmology continues to evolve at pace, staying ahead of the curve is more important than ever. From advances in imaging and AI integration to new frontiers in gene therapy and surgical techniques, innovation is reshaping the way clinicians diagnose and treat eye disease. With the second half of 2025 underway, we asked our  touchOPHTHALMOLOGY Future Leaders 2025 to share the developments they believe will shape the future of the field. Here, they highlight four exciting areas that look set to change practice – not only as the year draws to a close, but well into the future.

 

PTK-assisted customized epi-on cross-linking

ELZA-PACE-CXL (PTK-assisted customized epi-on cross-linking) represents a true paradigm shift in corneal therapeutics. By combining biomechanical stabilization with customized topographic reshaping in a single, epithelial-preserving procedure, we are achieving results that previously required multiple separate treatments — or were simply out of reach. As the technique becomes standardized and more widely published, it has the potential to redefine how we manage progressive keratoconus and other corneal irregularities.
Emilio Torres
ELZA Institute, Zurich, Switzerland
 AI-driven decision support tools

Looking ahead, an area that deserves more attention is the development of AI-driven decision support tools in ophthalmology. While AI has been widely explored for image analysis, the real challenge—and opportunity—is integrating AI into clinical workflows to support diagnosis, prognosis and treatment planning in a way that is reliable, explainable and equitable.

Maria Vittoria Cicinelli

Vita-Salute San Raffaele University, Milan, Italy

 

New spiral optics in multifocal IOLs

New spiral optics in multifocal IOLs as a potential alternative option to conventional diffractive optics are an exciting development to watch.
Jorge L Alió del Barrio

Vissum (Miranza Group)/Universidad Miguel Hernández Medical School, Alicante, Spain

 

 

 Advances in AMD and DME treatments

I’m particularly excited about the advances in long-acting drug delivery systems (Susvimo) and gene therapy. With new clinical data expected later this year, we may soon have better tools to reduce treatment burden for chronic retinal diseases like AMD and DME. At the same time, AI integration into electronic health records is becoming a reality, which could streamline workflows, flag high-risk patients, and guide personalized treatment, all within a real-world clinical environment. I am also particularly enthusiastic about robot-assisted retina surgery, though I believe it will still take a couple of years to become commercially available in our field.

                  Marina Roizenblatt

  Universidade Federal de São Paulo, Brazil


In case you missed it…
The first half of 2025 has seen exciting advances in ophthalmology. Discover which developments our touchOPHTHALMOLOGY Future Leaders 2025 consider the most impactful so far.

 


Citation: What’s next for ophthalmology in 2025? touchOPHTHALMOLOGY.com. 10 September 2025.

Learn more about the touchOPHTHALMOLOGY Future Leaders 2025 here.

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