The Role of Optical Coherence Tomography in the  Diagnosis of Early Age-related Maculopathy

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Sozinibercept: Is the Tide Turning for Better Visual Outcomes in Neovascular Age-related Macular Degeneration?

Sean Adrean

On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757636) and ShORe (OPT-302 with ranibizumab in neovascular age-related macular degeneration; ClinicalTrials.gov identifier: NCT04757610).2,3 These trials represent one of the largest phase […]

touchREVIEWS in Ophthalmology. 2025;19(1):Online ahead of journal publication

Sozinibercept: Is the Tide Turning for Better Visual Outcomes in Neovascular Age-related Macular Degeneration?

Sean Adrean

touchREVIEWS in Ophthalmology. 2025;19(1):Online ahead of journal publication

Imaging

< 1 min

The Role of Optical Coherence Tomography in the Diagnosis of Early Age-related Maculopathy

Ling Zhi Heng, Sobha Sivaprasad

Published Online: Jan 23rd 2013 European Ophthalmic Review, 2012;6(5):255-260 DOI: http://doi.org/10.17925/EOR.2012.06.05.255

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Abstract

Overview

There has been increasing interest in improving imaging technologies to identify and grade early age-related maculopathy (ARM).
Recently, advances in optical coherence tomography (OCT) has allowed a virtual biopsy of the retina and identification of different types of drusen in relation to early ARM. Several investigators have improved our understanding of both the qualitative and quantitative analyses of drusen, the clinical hallmark of ARM. The purpose of this article is to critically review the current literature inOCT in the evaluation of early ARM. Although seemingly useful and ideal, the current analysis of the retina using OCT is highly complex and lacking. It is currently too premature to use OCT as a grading tool for early ARM. However, the authors are hopeful that the rapid progress in this field will enable the use of an OCT-defined outcome measure in early ARM clinical trials in the foreseeable future.

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2 mins

Foreword: touchREVIEWS in Ophthalmology, Volume 17, Issue 2, 2023

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Sozinibercept: Is the Tide Turning for Better Visual Outcomes in Neovascular Age-related Macular Degeneration?

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Sozinibercept: Is the Tide Turning for Better Visual Outcomes in Neovascular Age-related Macular Degeneration?

The Role of Optical Coherence Tomography in the Diagnosis of Early Age-related Maculopathy

Abstract

Overview

Article

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Foreword: touchREVIEWS in Ophthalmology, Volume 17, Issue 2, 2023

Non-invasive Classification of Orbital Tissue Pathology Based on Texture Analysis Parameters from Magnetic Resonance Images

Optical Coherence Tomography Angiography

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Diabetic Macular Oedema and Retinal Imaging

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Emerging Star in Ophthalmic Imaging Technologies – OCT Angiography

Optical Coherence Tomography Angiography – A General View

Emerging Star in Ophthalmic Imaging Technologies – OCT Angiography

Optical Coherence Tomography Angiography of Choroidal Neovascularisation

Advances in Optical Coherence Tomography Angiography

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The Role of Optical Coherence Tomography in the Diagnosis of Early Age-related Maculopathy

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