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Corneal ectatic disorders, such as keratoconus, progressively weaken corneal integrity, leading to thinning, irregular astigmatism and visual deterioration.1 Typically progressive in nature, these ectasias result in increasingly thinner corneas, causing the cornea to protrude forward into a cone shape. This leads to increasing amounts of myopia and astigmatism – both regular and irregular – as the disease […]

EUROPEAN OPHTHALMIC REVIEW – VOLUME 14 – ISSUE 1 – SUMMER 2020

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Foreword

Welcome to this edition of European Ophthalmic Review, which features a wide range of highly interesting articles that reflect the rapid pace of today’s progress in ophthalmology. We begin with two of our popular expert interviews. First, Dominique Bremond-Gignac discusses the VEKTIS study, which has demonstrated the efficacy and safety of cyclosporine for the treatment of paediatric […]

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Expert Interviews

Dominique Bremond-Gignac, MD, PhD, FEBO, is Professor of Ophthalmology and Head of the Department of Ophthalmology with a paediatric and ocular surface subspecialty at the University Hospital Necker–Enfants Malades and University of Paris in Paris, France. She graduated in pharmacology and statistics (MSc) and completed her PhD thesis in anatomy. Her activity is distributed across […]

Surgical techniques for the correction of refractive errors include laser-assisted in situ keratomileusis (LASIK) and surface treatments, such as photorefractive keratectomy (PRK), transepithelial photorefractive keratectomy (TransPRK) and laser epithelial keratomileusis. These have become routine and reliable procedures with extremely high patient satisfaction rates;1 with safety, night vision and ocular comfort scores that rival or beat contact lenses.2 However, like […]

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Editorial

11 mins
Aamir A Aziz, Fawwaz A Siddiqui, Ibrahim Khanani

Modern treatments for wet age-related macular degeneration (wAMD) have progressed tremendously in the last decade, with the rise of anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections as the standard-of-care. Both aflibercept (Eylea®, Regeneron, Tarrytown, NY, USA) and ranibizumab (Lucentis®, Genentech, San Francisco, CA, USA) have become the gold standard for anti-VEGF agents. Initially, patients with […]

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Reviews

Glaucoma causes an optic neuropathy and is one of the leading causes of blindness globally.1 Pathologically, patients with glaucoma typically develop irreversible characteristic field defects due to loss of retinal ganglion cells and subsequent characteristic optic nerve-head damage. The main risk factor for development of glaucoma is intraocular pressure (IOP), reduction of which is targeted by […]

20 mins
Ashwini Kini, Mangayarkarasi Thandampallayam Ajjeya, Padmaja Sudhakar

Nonorganic vision loss (NOVL) or functional vision loss (FVL) is the presence of abnormal vision, or visual fields, without an organic pathology, despite a thorough and comprehensive evaluation. The symptoms will be inconsistent with the results of an objective examination.1–3 In some cases, vision loss is intentionally feigned, while in others it occurs under unconscious conditions. […]

10 mins
Lampros Lamprogiannis, Daisy MacKeith, Anthony J Vivian

The term amblyopia, derived from the Greek words α’µβλυ’ς (weak) and ω˛″ψ (eye), is defined as a unilateral (or, less commonly, bilateral) reduction of visual acuity as a result of inadequate visual experience during early life, which leads to a disruption of the normal visual neurodevelopment process.1 It is associated with anisometropia, ametropia, stimulus deprivation, strabismus and nystagmus, and it […]

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