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The World Cornea Congress IX, held from March 20–22, 2025, in Washington, D.C., brought together over 1,200 ophthalmologists to explore the latest in corneal disease and surgery. Held every five years, the event featured symposia, scientific sessions, exhibits, and networking, with a focus on advances in corneal transplantation. In this Q&A, Prof. M Vanathi, Professor of Ophthalmology at the All India Institute of Medical Sciences, New Delhi, shares insights on the role of therapeutic keratoplasty in treating severe corneal infections, surgical planning, and future directions in this vision-saving procedure.
Age-related macular degeneration (AMD) is one of the main causes of irreversible vision loss in ageing populations worldwide.1 In 2019, the US recorded 1.49 million people aged 40 years or older with late-stage AMD, reflecting a crude prevalence rate of 0.94%.2 Geographic atrophy (GA), ...
The treatment options for neurotrophic keratitis (NK) are ever-evolving as the pathogenesis of this increasingly prevalent degenerative keratopathy is further elucidated. Currently available therapeutics can be divided into medical, procedural and surgical interventions that directly address the effects of corneal ...
The RESTORE trial (NCT04945772) is a phase 2b randomized, sham-controlled, multi-centre, multi-dose, double-masked clinical trial evaluating the efficacy and safety of MCO-010 optogenetic therapy in adults with retinitis pigmentosa. MCO-010 is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy for ...
Retinitis pigmentosa is an inherited retinal dystrophy (IRD) caused by the loss of photoreceptors and characterized by retinal pigment deposits visible on fundus examination. Retinitis pigmentosa is the most common group of IRD. It was a pleasure to speak with ...
The National Diabetes Statistics Report 2020 estimates that of the 34.1 million adults in the USA with diabetes in 2018, 21.4% had undiagnosed disease.1 Due to an insidious disease course, diabetic complications like diabetic retinopathy (DR) are common. Among US diabetic adults, 28.5% have DR ...
Prof. Peter Stalmans (University Hospitals, Leuven, Belgium) talked us through his presentation at EURETINA on first reported clinical results from end-stage retinitis pigmentosa patients implanted with an innovative 3D neural interface retinal prosthesis. Questions Could you give us an overview ...
Continuing with our Ophthalmologist Power List series, we have an interview from Professor Jod Mehta. Prof Mehta of the Singapore National Eye Centre was named one of the emerging leaders in the 2019 Power List. We recently caught up with Prof ...
Fuchs endothelial dystrophy (FED) is a corneal endothelial disease characterised clinically by corneal endothelial dysfunction and guttae excrescences on the posterior corneal surface. The guttae excrescences represent foci of thickened posterior collagenous layers. The demise of healthy corneal endothelial cells (...
Intravitreal Pharmacotherapy in the Treatment of Retinitis Pigmentosa-related Cystoid Macular Oedema
Retinitis pigmentosa (RP) is an inherited retinal dystrophy characterised with the progressive loss of photoreceptors.1,2 Night blindness together with the peripheral visual field loss is the most prominent clinical feature.1,2 Central vision is relatively spared up to the later stages ...
Glaucoma is the most common form of optic neuropathy and a leading cause of blindness worldwide.1 Currently, no treatment is available to reverse glaucomatous retinal ganglion cell (RGC) damage or vision loss. In clinic, glaucoma is diagnosed by optic disc ...
Endophthalmitis is a severe inflammation of the interior of the eye caused by the introduction of contaminating micro-organisms following trauma, surgery, or hematogenous spread from a distant infection site. It may be categorized by clinical course (acute versus chronic), by ...
Age-related macular degeneration (AMD) is a progressive, noncurable disease primarily affecting the elderly. In addition to age the most important single contributing factor to the condition is an individual’s genetic makeup. As with many diseases, genetic predisposition greatly increases ...
The benefits that patients expect from cataract surgery have increased with time. For many patients a better quality of life depends on higher spectacle independence. Ideally, we would provide them with perfect vision at all distances, in all lighting conditions, ...
“Look… Up in the sky… It’s a bird… It’s a plane… No, it’s supertechnology.” Commonly performed in Europe, South Africa, Canada, and China, corneal collagen cross-linking (CXL) is still off-label in the US. Why? Despite the proven ...
Diabetes is a metabolic disease resulting from the body’s insufficient production or use of insulin, a peptide hormone responsible for regulating glucose levels in the blood and tissues. Especially when improperly managed, diabetes results in a number of complications ...
Introduction Introduction For almost 100 years, penetrating keratoplasty (PK) was the mainstay of therapy for patients with corneal endothelial disorders.1 That changed in 1998 with the introduction of posterior lamellar keratoplasty (PLK),2–4 later popularized in the United States as deep lamellar endothelial ...
AbstractThe rates of post-operative endophthalmitis have been low for many years, but recent reports suggest that this type of ocular infection may be on the rise. Fluctuations in the number of cases appear to correlate with the type of intraocular ...
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