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The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part ...
Age-related macular degeneration (AMD) is one of the main causes of irreversible vision loss in ageing populations worldwide.1 In 2019, the US recorded 1.49 million people aged 40 years or older with late-stage AMD, reflecting a crude prevalence rate of 0.94%.2 Geographic atrophy (GA), ...
The term ‘artificial intelligence’ was coined by a group of scientists during a workshop known as the “Dartmouth Summer Research Project on Artificial Intelligence” in 1956.1 The concept was based on the idea that “intelligent human behavior consisted in processes that ...
Article highlights Artificial intelligence (AI) represents a powerful way of analysing a large amount of data, extracting those features characterizing a given disease or condition. AI-based models have been largely tested in the main retinopathies, including age-related macular degeneration, diabetic ...
The RESTORE trial (NCT04945772) is a phase 2b randomized, sham-controlled, multi-centre, multi-dose, double-masked clinical trial evaluating the efficacy and safety of MCO-010 optogenetic therapy in adults with retinitis pigmentosa. MCO-010 is an ambient-light activatable Multi-Characteristic Opsin (MCO) optogenetic therapy for ...
Retinitis pigmentosa is an inherited retinal dystrophy (IRD) caused by the loss of photoreceptors and characterized by retinal pigment deposits visible on fundus examination. Retinitis pigmentosa is the most common group of IRD. It was a pleasure to speak with ...
Acanthamoeba is an opportunistic, unicellular, free-living protist with at least 25 species and 23 genotypes so far identified (on 18S rRNA sequencing).1 Organisms have a two-stage life cycle: metabolically active trophozoites and quiescent double-walled cysts. Both trophozoites and cysts are small, usually 15–50 µ...
Epidemiology According to data collected by the Centers for Disease Control and Prevention (CDC), as of December 2020, there have been over 16 million cases of coronavirus disease (COVID-19) in the USA alone, resulting in over 300,000 reported deaths. Worldwide case numbers stand ...
Prof. Peter Stalmans (University Hospitals, Leuven, Belgium) talked us through his presentation at EURETINA on first reported clinical results from end-stage retinitis pigmentosa patients implanted with an innovative 3D neural interface retinal prosthesis. Questions Could you give us an overview ...
In December 2019, authorities in Wuhan, China reported the first case of COVID-19, the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).1 Although coronaviruses are common pathogens in humans, the SARS-CoV-2 variant is particularly virulent. Disease transmission occurs ...
Diabetic macular oedema (DMO) is a complication of diabetic retinopathy and is a leading cause of blindness in working-age adults in developed nations. In 2015, there were an estimated 415 million people with diabetes worldwide.1 This number is predicted to rise to 642 ...
Cataract is the most common cause of blindness (accounting for 51% of blindness) and cataract surgery involving removal of fogged lenses and replacement with synthetic intraocular lenses is one of the most common surgical procedures performed worldwide.1,2 This intervention is hugely ...
Inherited retinal dystrophies (IRD) are genetic disorders characterised by variable, albeit progressive degeneration of the retina, retinal pigment epithelium (RPE) and choriocapillaris (CC).1,2 Prevalence varies in different countries, affecting approximately 1 in 4,000 individuals, with symptoms including poor peripheral or night vision, ...
Keratoconus is an ectatic corneal disorder characterized by a change in the organization and structure of the cornea. It is usually progressive and bilateral but asymmetrical. Keratoconus usually manifests during adolescence and early adulthood.1 Riboflavin-ultraviolet-A (UVA) cross-linking (CXL) is a ...
Retinal disease is a major cause of poor vision especially in the ageing population, and age related macular degeneration is the main cause of vision loss in the developed world.1,2 Early recognition of the signs and symptoms of retinal disease ...
Intravitreal Pharmacotherapy in the Treatment of Retinitis Pigmentosa-related Cystoid Macular Oedema
Retinitis pigmentosa (RP) is an inherited retinal dystrophy characterised with the progressive loss of photoreceptors.1,2 Night blindness together with the peripheral visual field loss is the most prominent clinical feature.1,2 Central vision is relatively spared up to the later stages ...
Diabetic macular oedema (DMO) is the leading cause of acquired visual loss in the working age population.1 There are estimated to be 21 million people with DMO globally,2 with numbers expected to rise as diabetes becomes more common and life expectancy ...
Welcome to the latest edition of European Ophthalmic Review, covering a variety of topics from all areas of ophthalmology. This edition features four articles within my specialty of retinal disease and imaging. Diabetic macular oedema (DMO) is the leading cause ...
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