The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part ...

Choroidal granuloma is a relatively rare manifestation of sarcoidosis. Cases of sarcoid granuloma may lack accompanying ocular inflammation and can mimic posterior segment tumours, leading to a delay in diagnosis and treatment. These lesions are typically steroid responsive,1 and quick ...

Giant cell arteritis (GCA) is a medium-to-large vessel vasculitis that affects branches of the thoracic aorta, including the carotid artery.1–4 The most feared ophthalmic complication is blindness (seen in up to ~25% of cases) due to arteritic ischaemic optic neuropathy involving ...

The importance of objective and quantitative measurement methods in uveitis – laser flare photometry Carl P Herbort Jr Centre for Ophthalmic Specialised Care at Clinic Montchoisi Teaching Centre, Lausanne, Switzerland; University of Lausanne, Lausanne, Switzerland Laser flare photometry (LFP) involves measuring ...

Uveitis comprises a range of intraocular inflammatory conditions of both infectious and non-infectious origin that can result in irreversible ocular damage and impaired vision or blindness.1 Effective management is therefore vitally important to prevent ocular damage and preserve visual acuity ...

Scleritis refers to a heterogeneous group of diseases characterized by inflammation of the sclera, which may also involve the cornea, adjacent episclera, and underlying uveal tract.1 In contrast to episcleritis, scleritis is associated with significant ophthalmic and systemic morbidity.2 Patients ...

Cytokines are not only critical for host defense and immunoregulation, but are also major players in the immunopathogenesis of inflammatory and autoimmune diseases. Janus kinases (JAKs) are critical for the intracellular signaling of a large family of cytokines. Tofacitinib (CP-690,550) ...

Avascularity of the cornea optimises its optical performance and also helps confer it immunological privilege.1 Loss of this immune privilege leads to poor survival of corneal grafts.2 Corneal new vessels (NVs) can also lead to oedema, lipid deposition, inflammation and ...

Birdshot Birdshot chorioretinopathy (BCR) is a bilateral, posterior uveitis that accounts for 0.6–1.5% of patients seen for uveitis in large referral centres and 6–7.9% of patients with posterior uveitis.1 Birdshot Birdshot chorioretinopathy (BCR) is a bilateral, posterior uveitis that accounts for 0.6–1.5% of ...