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Encouraging results have emerged from two phase II clinical trials investigating a novel treatment, PER-001, for glaucoma and diabetic retinopathy, two of the most common causes of blindness globally. Delivered via a sustained-release intravitreal implant every six months, PER-001 improved both vision and retinal structure compared with control groups.
In this expert Q&A, we speak with Dr Samir Jabbour, Assistant Clinical Professor at the University of Montreal and Adjunct Clinical Professor at McGill University, who also practices at the Centre hospitalier de l'Université de Montréal (CHUM) and Jewish General Hospital (JGH). Dr Jabbour shares insights from his presentation on the evolving role of combining refractive procedures with corneal crosslinking (CXL) for patients with keratoconus and post-refractive ectasia. He discusses clinical indications, patient selection, benefits and risks of simultaneous versus sequential approaches, and the technologies driving the next wave of personalized corneal treatments.
The American Academy of Ophthalmology (AAO) 2024 meeting in Chicago showcased many advancements in retinal research that show promise for the future.
The uvea is a vascular stratum that includes the iris, ciliary body and choroid. Uveitis is defined as inflammation of a part of the uvea or its entirety, but it is also used to describe inflammatory processes of any part ...
We are pleased to present the latest edition of touchREVIEWS in Ophthalmology. In this issue, we offer a series of engaging editorials, in-depth review articles and insightful original research highlighting some of the latest breakthroughs, innovations and practical insights in ...
Age-related macular degeneration (AMD) is a chronic deterioration and dysfunction of the outer retinal tissue and Bruch’s membrane (BrM). It is the leading cause of vision loss in people older than 60 years and is estimated to affect 288 million people ...
Dry eye disease (DED) is a prevalent ocular condition characterized by discomfort, visual disturbances and tear film instability due to insufficient tear production or rapid tear evaporation.1 With an increasing global incidence (i.e. up to 50%) and its significant impact ...
Thyroid eye disease (TED) is an autoimmune condition that can lead to significant visual impairment, facial disfigurement and decreased quality of life. It affects 16 out of every 100,000 females and 2.9 out of every 100,000 males. Risk factors for TED include age, female ...
Contrast sensitivity (CS), which is an important element of functional vision, helps in differentiating an object from its background. CS affects several aspects of vision, such as acuity, dark adaptation, visual field, motion detection and pattern recognition.1 A decline in ...
Retinal pharmacotherapy encompasses various drug delivery routes that offer potential avenues for effective treatment (Figure 1). Among these, intravitreal injections have emerged as the predominant method employed in clinical practice.1 They have established themselves as the primary approach for administering anti-vascular ...
The term ‘artificial intelligence’ was coined by a group of scientists during a workshop known as the “Dartmouth Summer Research Project on Artificial Intelligence” in 1956.1 The concept was based on the idea that “intelligent human behavior consisted in processes that ...
Mydriasis physiology Mydriasis refers to physiologic or pharmacologic pupillary dilation. Physiologic pupillary dilation occurs naturally as a response to low light and viewing objects in the distance. This process is mediated by both the iris sphincter and the iris dilator ...
Article highlights Artificial intelligence (AI) represents a powerful way of analysing a large amount of data, extracting those features characterizing a given disease or condition. AI-based models have been largely tested in the main retinopathies, including age-related macular degeneration, diabetic ...
Welcome to the latest edition of touchREVIEWS in Ophthalmology. In this edition, we feature a range of reviews and editorials on various diseases, including glaucoma and ocular surface disease, to name but a few, discussing improvements in our understanding and ...
The treatment options for neurotrophic keratitis (NK) are ever-evolving as the pathogenesis of this increasingly prevalent degenerative keratopathy is further elucidated. Currently available therapeutics can be divided into medical, procedural and surgical interventions that directly address the effects of corneal ...
Choroidal granuloma is a relatively rare manifestation of sarcoidosis. Cases of sarcoid granuloma may lack accompanying ocular inflammation and can mimic posterior segment tumours, leading to a delay in diagnosis and treatment. These lesions are typically steroid responsive,1 and quick ...
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