We are delighted to share the latest issue of touchREVIEWS in Ophthalmology, showcasing a diverse range of articles that highlight the innovation, interdisciplinary collaboration and continued advances driving progress in eye care today. We begin this issue with an important ...
A pioneering gene therapy has shown promising results in restoring sight in young children with AIPL1-associated severe retinal dystrophy—an ultra-rare genetic condition that causes profound sight impairment from birth and, until now, had no existing treatment. The findings, published in The Lancet, mark a major step forward in tackling inherited blindness.
On 28 May 2024, enrolment in phase III clinical trials for sozinibercept in neovascular age-related macular degeneration (nAMD) was completed.1 These trials include two large multicentre, double-masked, randomized controlled trials (RCTs): COAST (OPT-302 with aflibercept in neovascular age-related macular degeneration; ClinicalTrials.gov ...
The FDA has approved Susvimo® (ranibizumab injection) 100 mg/mL for the treatment of diabetic macular edema (DME). Susvimo is the first and only FDA-approved treatment shown to maintain vision in people with DME while requiring fewer treatments than standard-of-care eye injections.
Outlook Therapeutics has announced the 12-week efficacy and safety results from the NORSE EIGHT clinical trial evaluating ONS-5010 (bevacizumab-vikg) for the treatment of wet age-related macular degeneration (AMD).1 The findings were presented at the Hawaiian Eye and Retina 2025 Meeting.
In this interview, Dr SriniVas Sadda, Director of Artificial Intelligence & Imaging Research at the Doheny Eye Institute, and Professor of Ophthalmology at the University of California – Los Angeles (UCLA) Geffen School of Medicine, and President of ARVO (2024-2025), discusses the pressing challenges and emerging opportunities in treating retinal diseases. Despite progress, many conditions, such as inherited retinal disorders, macular degeneration and diabetic retinopathy, still lack effective treatments. Dr Sadda shares the latest advancements in diagnostic tools like imaging, which provide a deeper understanding of these diseases at the cellular level and emphasizes the need to expand access to eye care, particularly as the aging population and conditions like diabetes drive up demand. Dr Sadda also highlights ARVO’s role in uniting researchers, clinicians and engineers worldwide to foster collaboration and accelerate progress in addressing these critical issues in vision health.
The EURETINA 2024 Congress, held in Barcelona from September 19-22, brought together leading experts in ophthalmology to share the latest research and innovative treatments for retinal diseases. Among the highlights were several late-breaking abstracts that showcased promising advances in therapeutics for conditions such as retinopathy of prematurity (ROP), diabetic retinopathy (DR) and age-related macular degeneration (AMD). These studies not only demonstrated the efficacy and safety of novel treatment options but also addressed critical unmet needs in reducing patient burden and improving long-term outcomes.
We are pleased to present the latest edition of touchREVIEWS in Ophthalmology. In this issue, we offer a series of engaging editorials, in-depth review articles and insightful original research highlighting some of the latest breakthroughs, innovations and practical insights in ...
Age-related macular degeneration (AMD) is a chronic deterioration and dysfunction of the outer retinal tissue and Bruch’s membrane (BrM). It is the leading cause of vision loss in people older than 60 years and is estimated to affect 288 million people ...
Contrast sensitivity (CS), which is an important element of functional vision, helps in differentiating an object from its background. CS affects several aspects of vision, such as acuity, dark adaptation, visual field, motion detection and pattern recognition.1 A decline in ...
Neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DME) are two leading causes of visual impairment and blindness in the USA.1,2 Faricimab is the first bispecific antibody approved by the US Food and Drug Administration in ophthalmology and was ...
Age-related macular degeneration (AMD) is one of the main causes of irreversible vision loss in ageing populations worldwide.1 In 2019, the US recorded 1.49 million people aged 40 years or older with late-stage AMD, reflecting a crude prevalence rate of 0.94%.2 Geographic atrophy (GA), ...
Welcome to the latest edition of touchREVIEWS in Ophthalmology, and my first as the journal’s Editor-in-Chief. In this issue, we are delighted to present a series of compelling articles providing insights into some of the cutting-edge developments in this ...
Retinal pharmacotherapy encompasses various drug delivery routes that offer potential avenues for effective treatment (Figure 1). Among these, intravitreal injections have emerged as the predominant method employed in clinical practice.1Â They have established themselves as the primary approach for administering anti-vascular ...
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